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Acetone is both natural and synthetic. Too much acetone in the body can lead to acetone poisoning. Read this article to know more about this in detail.

Acetone is a byproduct of human and animal fat metabolism. Our human body uses glucose for energy. When there is less intake of carbohydrates or when there is a lack of insulin to move the glucose from the bloodstream into the cells, fat is used for producing energy. Ketone is produced as a byproduct of the fat metabolism that happens in the liver. Of all the ketones produced in the body, acetone is the most important. When you get all your energy from fat, there is excess production of ketones, and the resulting state is called ketosis. In diabetic patients, ketoacidosis can occur, which is a life-threatening complication due to ketone accumulation in the blood. While in some people who are on a low-carbohydrate diet, nutritional ketosis occurs that might help in weight loss.

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In addition to being present in the body, acetone is also seen in nature and many household products. Acetone is a solvent that is used in nail polish removers, paint removers, varnish removers, and also to remove grease from wool. It is released from trees, volcanoes, forest fires, exhaust from cars, tobacco, and landfills.

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Anything that is within limits is good. But when it exceeds, problems occur. The liver can only break down a certain amount of acetone. Acetone toxicity occurs when too much acetone builds up in the body, and the liver is unable to break it down.

Since the body can break down significant amounts of acetone, toxicity that can happen with acetone is infrequent. The chances of acetone toxicity are seen only when there is inhalation and ingestion of large amounts of acetone within a short span of time.

When the liver breaks down too much fat, ketone accumulation occurs in the body, which results in a condition called ketoacidosis. There are about three different types of ketone bodies synthesized during fat metabolism, and acetone is an important ketone. Ketoacidosis is a condition with dangerous complications. This is much more common in people with uncontrolled diabetes.

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Acetone toxicity is associated with fatal complications. However, it can also produce mild symptoms. The following are the mild to severe symptoms of acetone toxicity:

Prolonged exposure to acetone can result in dryness, redness, and cracks in the skin. When acetone comes in contact with the eyes, it can result in soreness, redness, and tearing in the eyes. Acetone is not a potential carcinogen and cannot cause cancer.

1. Although it can be weird to hear, acetone toxicity produces a fruity odor in your breath. This is because of the accumulation of ketones that have occurred in the bloodstream. It is an important feature that helps in the diagnosis of acetone toxicity.

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Under normal circumstances, ketones are not seen in the urine. But when acetone toxicity occurs, urine shows the presence of ketones which can help in the diagnosis.

When you reach out to the doctor within a few minutes of ingestion, acetone can be cleared from your stomach by stomach pumping. In this procedure, a tube is inserted into the stomach through the throat. Through this tube, water and saline are injected into the stomach, and the contents are sucked back until the acetone present in the stomach is fully sucked out. An important disadvantage of this technique is when the tube enters the lung instead of the stomach, the saline and water injected can result in aspiration pneumonia leading to the death of the individual. Also, stomach pumping is possible only when the patient is taken to the hospital in a few minutes. When it is past an hour, this technique is not of use because acetone gets absorbed quickly.

There is no treatment available for acetone toxicity, and treatment mainly aims at providing supportive care. Your system naturally tries to remove these acetones from the body. When there is an accumulation of acetone in the blood, there is rapid breathing which is a defense mechanism of the body to eliminate the acetones. In such cases, intubation is done to help you with breathing. Intravenous fluids and blood pressure support may be necessary.

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Do not try to vomit the contents of your stomach if you have drunk large amounts of acetone because it can damage the mucosa of the oral cavity and esophagus.

Ketoacidosis that happens within the human body can be prevented by keeping your diabetes in control. Do adequate lifestyle and dietary modifications along with medications and keep your sugar level in control to prevent the accumulation of ketones in the body.

Acetone is a liquid that has its use in many household items. When used within limits, it can be highly beneficial. Use acetone carefully so as to prevent acetone toxicity. Also, if you are a diabetic individual, keep your sugar levels in check to prevent ketoacidosis.

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Acetone is a clear liquid that has a unique smell. Products like nail polish, paint, varnish, and other cleaning agents contain acetone. Acetone is found in humans, as a by-product of fat metabolism. The excess buildup of acetone to the level at which the liver finds it difficult to break it down leads to severe acetone toxicity. A level of 10 to 20 L does not cause severe effects. However, levels above 50 L are considered toxic. It damages the central nervous system and also leads to kidney damage, gastrointestinal disorders, etc.

Acetone is a non-inflammatory gas. The carbohydrates which we eat are broken down in the body to produce energy. When carbohydrate intake is reduced, the body breaks down the fat to release energy. Ketones are produced as a by-product of fat metabolism. When excess fat is broken down for energy production, ketones get accumulated in the body. Acetone is an important type of ketone; on excess levels, it causes toxic effects in the body.

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Accidental exposure to acetone-containing agents and ingesting nail polish, and rubbing alcohol that contains acetone also lead to acetone toxicity in humans.

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Acetone is clear gas and human get exposed to it in various forms. When exposed to a little amount of acetone, the liver breaks it down. When high amounts are swallowed or inhaled it leads to the following:

Exposure to acetone occurs through respiration or ingestion. The acetone then enters the bloodstream from the lungs or stomach. The little amounts of acetone are easily broken down in the liver into harmful chemicals. Most of the acetone is expelled back into the air by the lungs. Only a few amounts of acetone are excreted in the urine. The time taken by the body to clear off the acetone depends on the exposure time and acetone concentration. Once the exposure to acetone is limited, the acetone leaves the body within three days.

Acetone found in paints, nail polish remover, and other cleaning agents is accidentally inhaled for a long time. It leads to the following-

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Acetone or dimethyl ketone is a colorless liquid with a fruity odor. It is present in nail polish, rubbing alcohol, and other cleaning agents. Accidental exposure to such products leads to various toxic effects as it is easily absorbed by the skin. Acetone is also found to evaporate from water and soil into the atmosphere. It is then broken down into gas form (methane and ethane) by the ultraviolet (UV) light. The human body tries to excrete the acetone by rapid breathing and by peeing. Vomiting after ingesting acetone is a bad option, as it can erode the mucosa of the mouth and food pipe. The doctor may advise stomach pumping immediately after the acetone ingestion to suck out the acetone from the stomach, but it has its own disadvantages. The healthcare specialist also suggests intravenous fluids to maintain the blood pressure.

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Acetone toxicity happens due to intake of acetone-containing nail polish, rubbing alcohol, or when excess acetone accumulates in the body due to fat metabolism. The organs that are affected by acetone toxicity are:

Humans are exposed to acetone that is present in paints, varnish, cleaning agents, and other products (nail polish). Exposure to the high concentration and for prolonged periods leads to various toxic effects. The skin absorbs the liquid form of acetone on prolonged exposure. The skin gets cracked, irritated, and dry on acetone exposure. It is prevented by avoiding cleaning agents, nail polish remover, paints, and other products that contain acetone.

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When the skin becomes exposed to acetone-containing products, it becomes dry, irritated, and cracked. As soon as the skin is exposed to such toxic chemical, the following are done:

Certain nail polish and the nail polish remover contain a high concentration of acetone. On exposure to acetone containing nail polish, the following effects occur:

Urine test: Generally, ketones (acetone) are not found in the blood. But acetone is excreted in the urine if excess levels are present in the blood.

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Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have

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